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Panel A: Fluorescence labeling of nuclei, Panel B: Phase imaging. The arrows point to cells in the M phase, clearly visualized with both fluorescence and phase imaging.

Determination of miotic phase of cells using Phasics QPI camera

Nov. 15, 2021

At the frontier of photonics, biology and artificial intelligence lies the future of life science. In a recent paper from the Université Côte d'Azur, researchers combine Quantitative Phase Images with a new supervised autoencoder to classify cells population based on the cell cycle. Images acquired with a Phasics SID4Bio QPI camera allows to increase the classification accuracy of cells present in the mitotic phase of the cell cycle.

Read the full article here: https://hal.archives-ouvertes.fr/hal-03364377

Learn more about PHASICS applications in life science here: https://www.phasics.com/en/application-markets/microscopy/life-science/

In the illustration (courtesy of Philippe Pognonec, Axel Gustovic, Zied Djabari, Thierry Pourcher, Michel Barlaud): 

  • Panel A: Fluorescence labeling of nuclei,
  • Panel B: Phase imaging. The arrows point to cells in the M phase, clearly visualized with both fluorescence and phase imaging. 

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